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0 votes
1 reply
123 views
in silico vaccine design
vaccine insilico
updated by dthorbur 350 • | written by lamiajerishubah 0
0 votes
0 replies
70 views
News: Online course: Machine Learning for Multi-Omics Integration (21–23 September)
omicsintegration machinelearning multiomics
updated by GenoMax 16K • | written by Physalia-courses 281
0 votes
2 replies
261 views
Forum: Real-world adoption of AI/ML in bioinformatics workflows: Questions from a junior researcher
bioinformatics machine-learning career discussion artificial-intelligence
updated by i.sudbery 2.3K • | written by oguzhanisilay 0
0 votes
1 reply
158 views
Correct way of doing enrichment analysis (ORA)
enrichment analysis transcriptomics over representation
updated by i.sudbery 2.3K • | written by carolofharvest 6
0 votes
0 replies
40 views
Tool: hlaconcord — harmonize & cross-check HLA typing across OptiType / arcasHLA / HLA-LA / HLA-HD
software ngs hla-typing tools hla
written by Leon 0
0 votes
2 replies
194 views
HaplotypeCaller parameter `--ploidy-regions` regarding the PAR regions on XY chromosomes
gatk haplotypecaller par
written by Xiaokang 8
0 votes
2 replies
185 views
Brain datasets
rnaseq neuroscience brain dataset
updated by ATpoint 9.1K • | written by aj123 14
1 vote
2 replies
189 views
How can I conduct a secondary analysis of HLA gene genomic variation across different geographic and ethnic populations, such as American, European, South Asian, and Mongolian populations?
data genomic analysis
updated by dthorbur 350 • | written by backupdata 1
2 votes
3 replies
269 views
Can someone explain why are my Gnomad WGS AFs often 10x the Gnomad WES AF
frequencies gnomad allele
updated by Jeremy Leipzig 2.3K • | written by stuart archer 18
0 votes
1 reply
157 views
clusterProfiler GSEA (gseGO/gseKEGG): full ranked list vs DEG list, BH correction, and GO collapsing under FDR
go kegg gsea clusterprofiler
updated by Arup Ghosh 402 • | written by ki 0
1 vote
0 replies
73 views
News: Pavel Pevzner to give an invited talk at CIBB 2026 (Rome, Sept 2-4)
bioinformatics biostatistics ai machine-learning
written by Umberto 1
0 votes
0 replies
66 views
Tool: BioArena: blind comparison arena for AI models on biomedical questions
benchmarking bioinformatics ai llm tool
written by Rong 0
0 votes
1 reply
103 views
Troubleshooting an MLPA-confirmed OPA1 exon duplication missing in ONT Long-Read SV callers (cuteSV/Sniffles)
cnv nanopore structural-variation variant-calling mlpa
updated by colindaven 844 • | written by Kevin 0
0 votes
3 replies
272 views
WGS-based SNP phylogeny - how to include accessions from an outgroup species
outgroup snp vcf phylogeny wgs
updated by colindaven 844 • | written by maxrwjones 7
0 votes
4 replies
1.8K views
Python deconvolution tools for bulk RNA-seq data
rna-seq bulk-rna-seq deconvolution python transcriptomics
updated by Bernhard 0 • | written by AlexStar 22
0 votes
12 replies
752 views
R1 / R2 are out of sync
pair proper
written by Jon 3
0 votes
0 replies
59 views
News: Workshop: Virtual ChIP-Seq / ATAC-Seq – July 28–30, 2026
virtual chipseq workshop atacseq uconn
written by zsc25001 1
0 votes
0 replies
66 views
News: Advanced Python for Data Science and Bioinformatics
machinelarning datascience python dataanalysis
written by Physalia-courses 281
0 votes
0 replies
92 views
Job: Postdoctoral Fellow in Single-Nucleus Studies of Psychiatric and Substance Use Disorders
bioinformatics
written by ejvandenoord 1
0 votes
2 replies
189 views
News: Webinar: Are your NGS workflows ready for GMP?
gxp gmp ngs
updated by Michael Dondrup 5.6K • | written by Nicole 12
0 votes
3 replies
292 views
Forum: Has online bioinformatics training replaced in-person courses?
in-person bioinformatics workshop online training
updated by Michael Dondrup 5.6K • | written by ecSeq Bioinformatics 9
0 votes
0 replies
64 views
News: Deep Learning for Evolutionary Genomics
evolutionarygenomics deeplearning
updated by GenoMax 16K • | written by coursesinfo 0
0 votes
0 replies
59 views
News: Population Genomics and Structure Analysis
population genomics
updated by GenoMax 16K • | written by coursesinfo 0
0 votes
0 replies
48 views
Tool: Biomedical Evidence Navigator: a free tool to pull a single gene/variant/disease evidence report from PubMed, GWAS Catalog, ClinVar & Open Targets
agent python biomedical tool
written by Tunahan 0
0 votes
0 replies
54 views
News: Webinar: Programming Biology with Genome-scale AI - 10 August - 3 PM CEST
genomics ai programming
updated by GenoMax 16K • | written by Physalia-courses 281
0 votes
1 reply
138 views
single cell
redisplay
updated by ATpoint 9.1K • | written by Victor 0
0 votes
3 replies
266 views
Why does MEGAHIT --min-contig-len 1 produce fewer long contigs than --min-contig-len 500 in a two-pass metagenomic assembly?
megahit metagenomics
updated by Ram 4.5K • | written by Sachin 2
0 votes
5 replies
324 views
Tool: HuskHoard – POSIX-transparent lazy loading for large Parquet/S3 datasets
storage
updated by GenoMax 16K • | written by jo 0
0 votes
4 replies
295 views
Best practices and parameter optimization for aligning highly degraded ancient S. mutans genomes?
bwa alignment variant-calling metagenomics ancient-dna
written by oguzhanisilay 0
0 votes
2 replies
173 views
SnpEff build fails with custom Saccharomyces cerevisiae database (R64-4-1) - Protein check "Not found" vs "OK" split
custom_database snpeff s.cerevisiae
updated by GenoMax 16K • | written by mohammaddaud046 0
2 votes
2 replies
1.6K views
pvalueCutoff for enrichGO, enrichKEGG and enrichDO does not seem to function properly
clusterprofiler
updated by Guillermo 3 • | written by t.mcgovern 2
9 votes
0 replies
229 views
Blog: Fable is not a useful model
anthropic ai safety
updated by LauferVA 497 • | written by Rob 747
0 votes
0 replies
64 views
News: Landscape Genomics course
populationgenomics landscapegenomics r
written by Physalia-courses 281
0 votes
0 replies
65 views
News: Instructor-led online training - Population Genomics and Structure Analysis
population genomics
updated by GenoMax 16K • | written by coursesinfo 0
0 votes
0 replies
86 views
Tool: Update: Jetomics v2.0 – Now with Local FASTQ Pipelines, Xenium Spatial Support, and Free Academic Licensing
rna-seq xenium spatial transcriptomics
written by Aram Donyaee 0
0 votes
5 replies
406 views
single cell processed data
single-cell
updated by marco.barr 22 • | written by Aya 0
0 votes
8 replies
18K views
How to load data into R from an external hard drive?
r load rstudio unix
updated by Dexter Watts 0 • | written by M.O.L.S 10
0 votes
1 reply
142 views
I need help clustering genes across different timepoints AND multiple tissues
advice help clustering
updated by manaswwm 64 • | written by mohammad.naweed 0
0 votes
3 replies
221 views
How can I visualize the Gene Ontology hierarchy for a set of GO terms in R?
ontology go plotting r
updated by Arup Ghosh 402 • | written by fnepo 4
10 votes
18 replies
12K views
Is There A Site Where Call For Papers And Conferences Are Listed In One Place?
papers conference
updated by James Michael Smith 0 • | written by Brandstaetter 27
0 votes
0 replies
87 views
Tool: Free IgGM Server
iggm antibody design
written by immunology_bishop 1
2 votes
12 replies
22K views
How to transpose large amounts of datasets in excel
transpose excel
updated by Ram 4.5K • | written by Vanceed 3
0 votes
0 replies
101 views
News: Why does every R tutorial work... Except on my own data?
tidyverse messydata r
written by Physalia-courses 281
0 votes
0 replies
116 views
Tool: Free browser tool: HPO interactive graph , clinical note to HPO terms (client-side, no PHI upload)
phenotype hpo clinical-nlp
updated by GenoMax 16K • | written by mchandrahasreddy 0
1 vote
4 replies
301 views
Ranking Seurat markers for annotation — are pct.1/pct.2 standard, or is log2FC + adjusted p-value enough
snrna sequencing clustering annotation
updated by GenoMax 16K • | written by Arindam 2
0 votes
3 replies
289 views
News: Free AI/ML for Genomics course with Colab notebooks, Geneformer, scVI, AlphaGenome
machine deep learning transformers
written by aadil 5
0 votes
8 replies
4.8K views
How to compute enrichment of one feature in the other across the genome (log fold, and pvalue)
genome enrichment
updated by eebloom 11 • | written by User 7754 29
0 votes
0 replies
67 views
News: (Workshop) RNAseq data analysis with R and Bioconductor
genesetenrichmentanalysis bioconductor rnaseq r
written by Physalia-courses 281
0 votes
0 replies
77 views
Tool: ctdR: enrichment analysis of chemical–gene interactions from the Comparative Toxicogenomics Database
ctd bioconductor enrichment r toxicogenomics
written by l.corsaro 0
0 votes
3 replies
240 views
Best practice for combining Ambient RNA correction and sc.pp.regress_out() in scRNA-seq
how-to scrna-seq ambient
written by messy_cat 0
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