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0 votes
6 replies
390 views
Looking for a database "This gene is expressed in that tissue"
expression gtex tissue gene
updated by sara • sara • written by Pierre Lindenbaum Pierre Lindenbaum
0 votes
4 replies
1.6K views
Illumina Infinium Human Global Screening Array manifest file
microarray illumina genotyping
updated by GenoMax GenoMax • written by Jichen Wen • Jichen Wen
0 votes
0 replies
84 views
Job: Director/Senior Director of Research Software Engineering
job
written by vanessa vanessa
0 votes
1 reply
122 views
Should QC cutoffs be done per-sample or one global cutoff for snRNA-seq with very different samples?
quality snrnaseq seurat control
updated by ATpoint ATpoint • written by dxj294 • dxj294
0 votes
0 replies
100 views
News: Single-cell analysis course & certification
singlecell bioinformatics rnaseq ngs
updated by GenoMax GenoMax • written by Nicole • Nicole
0 votes
4 replies
257 views
Gold standard / Phylogenetics for intertidal fish
phylogenetics intertidal busco orthologs
updated by samuel.a.odonnell samuel.a.odonnell • written by thrivenow • thrivenow
7 votes
2 replies
290 views
Tool: FindSSU — fast 16S/18S classification, comparison, and sequence retrieval for 276,000 organisms via website, API, or command-line tool
ssu 16s bbtools taxonomy
updated by Dunois • Dunois • written by Brian Bushnell Brian Bushnell
0 votes
0 replies
67 views
Tool: ALIEN: pure-Python GMT builder with MSigDB/Enrichr downloads for namespace-specific gene-set libraries
python gsea msigdb enrichr gmt
written by Denis Demin • Denis Demin
0 votes
3 replies
399 views
Dealing with massive CNV hyper-calling in DRAGEN Germline Enrichment: Best post-hoc VCF filtering and cohort collapse strategy?
cnv truvari whole-exome bcftools-filtering dragen
updated by LauferVA LauferVA • written by yawolberg • yawolberg
0 votes
0 replies
84 views
News: Agentic AI for Life Sciences – Online course (6–7 July)
genomics ai agenticai
written by Physalia-courses Physalia-courses
0 votes
1 reply
167 views
Tool: Exploring forensic STR matching from consumer WGS data (experimental pipeline)
genomics bioinformatics forensics
updated by jared.andrews07 jared.andrews07 • written by Spike Tree • Spike Tree
0 votes
0 replies
76 views
Tool: edge2torch — flexible PyTorch models for knowledge-primed neural networks
software python machine-learning neural-networks systems-biology
written by Thomas • Thomas
0 votes
1 reply
759 views
q-value threshold for omics data when performing univariate cox analysis
machinelearning q-value cox fdr omics
updated by i.sudbery i.sudbery • written by Yugan Gogul Muthukumar • Yugan Gogul Muthukumar
0 votes
0 replies
326 views
Job: Hiring: Full-Time & Part-Time Bioinformatics Researchers – University of Malta
bioinformatics academia multi-omics
written by jp jp
0 votes
1 reply
146 views
ROC Analysis for a Single Continuous Biomarker
roc auc biomarker learning machine
updated by i.sudbery i.sudbery • written by fnepo • fnepo
0 votes
3 replies
402 views
Addmodulescore permutation
integration seurat sctransform st
updated by jared.andrews07 jared.andrews07 • written by María José • María José
0 votes
0 replies
73 views
Tool: GeneFix AI – Open Source Bioinformatics AI Engine for Sequence Analysis, Research Assistance & AI Integration
bioinformatics
written by Mubashir • Mubashir
0 votes
0 replies
81 views
News: Introduction to Snakemake (SNKM03)
snakemake
updated by GenoMax GenoMax • written by oliverhooker oliverhooker
0 votes
0 replies
48 views
News: Final and Last Call - Only 3 Last Places Remaining for the 10th Berlin Summer School in NGS Data Analysis 2026
variantcalling transcriptomics summerschool dnaseq rnaseq
written by ecSeq Bioinformatics • ecSeq Bioinformatics
0 votes
0 replies
81 views
Job: Director/Senior Director of Research Software Engineering
engineering director research software
updated by colindaven colindaven • written by vanessa vanessa
0 votes
2 replies
235 views
Doublet Detection in SMART-Seq2 single-cell data
doublets scrnaseq singlecell smartseq2
written by luca8650 • luca8650
0 votes
0 replies
53 views
Variant counts decrease across cumulative coverage tiers after genotype masking
vqsr vcf bcftools wgs filtering
written by itsmesmb • itsmesmb
0 votes
0 replies
80 views
Can vg/minigraph-cactus export a GATK-style all-sites gVCF from a pangenome graph?
gvcf vg
written by RianeZ • RianeZ
0 votes
0 replies
57 views
Tool: VarGate > dataviz + scoring of QC metrics (Picard / biobambam2)
vargate
written by Pierre • Pierre
0 votes
0 replies
55 views
Opinions? Using Variable Inclusion Probability (VIP) as a bootstrapping approach to Elastic Net modeling
machine-learning omics elastic-net 16s bootstrap
written by Ana • Ana
0 votes
0 replies
71 views
News: Online course - Nextflow for beginners
workflowmanager nextflow
written by Physalia-courses Physalia-courses
5 votes
4 replies
5.2K views
Multiplexed Rnaseq
rna illumina gene
updated by Saurav • Saurav • written by Yannick Wurm Yannick Wurm
0 votes
0 replies
62 views
OTU filtering thresholds for soil ITS metabarcoding – none of my tested filters seem appropriate
metabarcoding soil edna its
written by Loïs • Loïs
0 votes
5 replies
1.3K views
How to handle TrEMBL proteins without gene annotation in plasma proteomics?
biomarker uniprot proteomics annotation trembl
updated by domanic • domanic • written by Luwell • Luwell
1 vote
1 reply
646 views
Advice on choosing the best ChromHMM mode for CUT Tag data
cut_tag chromhmm histone
updated by dsdsdsdsdsd • dsdsdsdsdsd • written by luminea • luminea
0 votes
1 reply
163 views
What repetitive bioinformatics task do you wish was fully automated?
automation discussion workflow pipeline
updated by Stefanie • Stefanie • written by Greeshma Reddy • Greeshma Reddy
0 votes
0 replies
561 views
About peptide design
software error
updated by Jimmy • Jimmy • written by fatema19.bge • fatema19.bge
0 votes
2 replies
1.3K views
multiple peptide docking
docking peptide
updated by Jimmy • Jimmy • written by husainbioinfos • husainbioinfos
0 votes
1 reply
570 views
Peptide Toxicity
protein toxinpred3.0 toxicity peptide
updated by Jimmy • Jimmy • written by Saurabh • Saurabh
2 votes
1 reply
110 views
Which locus should be considered the true ortholog after liftOver disagreement between chrUn and chr16 in canFam4 miRNA mapping?
genome-assembly mirna ucsc blat liftover
written by jhonatan.henrique • jhonatan.henrique
0 votes
1 reply
141 views
Tool: qPCR Analyst: browser-based qPCR analysis tool, no install required
gene-expression qpcr statistics visualization tool
updated by Ram Ram • written by qPCR Analyst • qPCR Analyst
0 votes
1 reply
150 views
Forum: should i come to bioinformatics (need help)
new help
updated by Ram Ram • written by mehulgautam600 • mehulgautam600
0 votes
0 replies
69 views
News: Spring School in Bioinformatics – Online Course, 8–12 June
singularity genomeassembly phylogenomics rnaseq
written by Physalia-courses Physalia-courses
0 votes
2 replies
3.1K views
Best way to systematically select ENCODE data to download?
encode
updated by Raquel Moya • Raquel Moya • written by Eric Lim Eric Lim
0 votes
0 replies
53 views
What is the best approach/workflow to map rMATS alternative splicing events to full-length isoforms?
rmats alternative splicing isoform rna-seq
written by mahsa80.mm • mahsa80.mm
0 votes
1 reply
122 views
Question about ONT basecalling
ont basecalling
updated by lieven.sterck lieven.sterck • written by Max • Max
0 votes
0 replies
70 views
Forum: Career Advice: Independent Institutional Project (Public Data) vs Entry-Level Industry Position
career industry job advice academia
updated by GenoMax GenoMax • written by eyaggelia146 • eyaggelia146
1 vote
2 replies
289 views
Tool: vcfv - fast VCF parser to Polars/Pandas DataFrame with native INFO and FORMAT expansion
polars python parser vcf
written by rvk20 • rvk20
4 votes
0 replies
294 views
Tutorial: Free beginner-friendly tutorial series for single-cell RNA-seq analysis (ngs101.com)
scrna-seq
written by ngs101.com ngs101.com
0 votes
0 replies
53 views
Identification of antisense transcripts and/or cryptic transcripts from Stranded total RNA-seq data
antisense transcripts totalrna-seq rnaseq cryptic
written by WannaBeWizard • WannaBeWizard
0 votes
0 replies
47 views
News: Seeking Feedback for CPOP V2, A GNN & Ensemble Platform for Catalytic miRNase Design
rna
updated by GenoMax GenoMax • written by Joshua • Joshua
0 votes
5 replies
3.6K views
how to distinguish monomer and dimer without wetlab techniques
sequence
updated by Gunjan • Gunjan • written by dineshtripathy9658 • dineshtripathy9658
0 votes
3 replies
251 views
Distribution of Transcripts per Cell in Spatial Transcriptomics (Xenium)
xenium spatial-transcriptomics spatialdata spatial-omics
updated by Bastien Hervé Bastien Hervé • written by npont • npont
2 votes
0 replies
96 views
News: 10 Years of Physalia Courses: Celebrating with a 10% Discount for the BioStar Community
training-courses genomics bioinformatics
written by Physalia-courses Physalia-courses
6 votes
3 replies
8.6K views
Tool: cnv_facets: somatic Copy Number Variant calling using the facets package
cnv somatic facets cancer
updated by yalin • yalin • written by dariober dariober
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