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0 votes
4 replies
369 views
Best approaches to identify pathways uniquely affected by different drugs?
pathway enrichment drugs transcriptomics
updated by ATpoint 9.1K • | written by fnepo 4
0 votes
1 reply
146 views
How should duplicate samples be handled when identifying super-enhancers?
macs2 superenhancer h3k27ac
updated by Bastien Hervé 680 • | written by G.J.W 0
0 votes
0 replies
74 views
News: Webinar- Target discovery in Alzheimer’s: Linking causal biology with CNS expression
alzheimers bioinformatics targetdiscovery drugdiscovery
updated by GenoMax 16K • | written by Nicole 12
4 votes
1 reply
492 views
News: Free interactive bioinformatics course with browser terminal simulator and real datasets
rna-seq tutorial python
updated by GenoMax 16K • | written by aadil 5
0 votes
3 replies
144 views
Is NeMO down for good?
databases
updated by GenoMax 16K • | written by mk 31
0 votes
1 reply
1.4K views
How to change the number of seeds/predictions run by Alphafold
alphafold protein-structure alphafold2 structure-prediction protein-prediction
updated by Matic Broz 1 • | written by umjpyw 0
0 votes
3 replies
247 views
Annotating spatial transcriptomic
spatial transcriptomic
updated by Bastien Hervé 680 • | written by Synat 0
0 votes
3 replies
302 views
Genome assembly from pooled individuals
pangenome plant genome genomics assembly
updated by colindaven 844 • | written by Anirmgls 0
0 votes
6 replies
353 views
Forum: How do you decide if course feedback is actually trustworthy?
trainings ngs feedback workshops
updated by GenoMax 16K • | written by ecSeq Bioinformatics 9
1 vote
6 replies
3.2K views
Boltz1 structure prediction software installation
boltz1
updated by Matic Broz 1 • | written by dsk129 1
0 votes
1 reply
721 views
Building a PC for BioML/ProteinDesign
protein-design machine-learning
updated by Matic Broz 1 • | written by iloveproteins 0
0 votes
1 reply
1.8K views
In molecular docking (autodock4), how to choose the best pose of docked state (from the clusters) for MD simulations?
autodock cluster
updated by Matic Broz 1 • | written by cnrahul 0
0 votes
0 replies
132 views
Job: Computational Postdoctoral Fellow (Quantitative Modeling Group) at Berkeley Lab, Berkeley, CA
metabolomics bioinformatics bioengineering biomanufacturing
written by BerkeleyLab 7
0 votes
2 replies
2.1K views
Problems separating and converting molecule files with openbabel
openbabel
updated by Matic Broz 1 • | written by smithk 0
2 votes
0 replies
84 views
News: Developing R/Bioconductor Packages for Genomics - 27-31 July 2026
genomics bioconductor r packages
written by Physalia-courses 281
1 vote
0 replies
98 views
Tool: Yet Another Boltz2 Server
folding protein pdb boltz2 alphafold
written by immunology_bishop 1
0 votes
2 replies
1.7K views
Problems in Molecular Docking in Autodock vina
atom boron autodock
updated by Matic Broz 1 • | written by Nibedita 0
0 votes
4 replies
6.3K views
Simple Molecular Docking
docking molecular
updated by Matic Broz 1 • | written by ericmajinglong 12
0 votes
0 replies
118 views
News: RNA-Seq Analysis (RNAA02)
rna-seq
updated by GenoMax 16K • | written by coursesinfo 0
0 votes
2 replies
2.5K views
Trouble with Ligand-Protein Docking in AutoDock Vina: Shows an error when docked against a new set of ligands
docking protein-receptor ligand-protein-docking autodock-vina
updated by Matic Broz 1 • | written by bandaru 0
0 votes
8 replies
471 views
Forum: Recommendation for laptop in bioinformatic
recommendation laptop hardware
updated by Ram 4.5K • | written by joe_mar02 0
0 votes
1 reply
1.3K views
AutoDock Vina Gives Different Results From Different Simulations Using Same Parameters, and Different From Experimental Results
screening vina docking virtual affinity binding autodock discovery drug
updated by Matic Broz 1 • | written by ac.research 3
0 votes
0 replies
127 views
Tool: ProteinIQ.io - browser-based bioinformatics tools for proteins, DNA, RNA, ligands, and structures
web bioinformatics free platform
written by Matic Broz 1
0 votes
3 replies
347 views
Job: Expert review request: lac operon binding site annotations for a regulatory grammar-decoding project
binding-site gene-regulation transcription-factor e-coli annotation
updated by Michael Dondrup 5.6K • | written by Gary 0
0 votes
10 replies
2.9K views
Java -xmx option does not limit memory usage in the ImputePipelinePlugin?
phg phg
updated by rakesh 0 • | written by twrl8 0
0 votes
0 replies
82 views
Tool: [Tool] spatial-cluster-compare — stop guessing which clustering algorithm to use on your spatial proteomics / cytometry data
python
written by mathis.bouvet 0
56 votes
76 replies
73K views
How To Efficiently Parse A Huge Fastq File?
fastq next-gen-sequencing
updated by jena 33 • | written by Panos 191
0 votes
0 replies
134 views
News: CIBB 2026 — Three free pre-conference satellite events + Registration open (Rome, Sept 1-4)
bioinformatics machine-learning news single-cell biostatistics
written by Umberto 1
0 votes
1 reply
161 views
1000 Genomes reference panels
panel reference
updated by Arup Ghosh 402 • | written by Shalini 2
1 vote
13 replies
9.1K views
Small molecule databases
cheminformatics moleculescreening
updated by Shuai 0 • | written by Sabine 7
0 votes
0 replies
117 views
Tool: ggwas: comprehensive ggplot2 toolkit for GWAS visualization (17 plot types, journal themes, smart downsampling
r ggplot2 manhattan-plot visualization gwas
written by Bartek 0
0 votes
0 replies
73 views
Tool: macsima-qc – quantitative QC for automated cell segmentation (Isolation Forest + KS test)
segmentation python macsima maciqview
written by mathis.bouvet 0
0 votes
0 replies
110 views
News: Large Language Models (LLMs) into your data anaylsis workflows using Python and R
python llms agenticai ai r
written by Physalia-courses 281
0 votes
0 replies
112 views
Tool: Free Metappuccino server for SRA metadata collecting
sra llm metappuccino
written by immunology_bishop 1
0 votes
4 replies
415 views
Forum: Recommendation and Advice
beginner learning
updated by immunology_bishop 1 • | written by Sabina 0
1 vote
8 replies
5.7K views
How to Detect Frameshifts in a Protein Alignment
frameshift mutation detection sequence alignment
updated by b.contreras.moreira 49 • | written by nickeener 7
0 votes
20 replies
3.3K views
Poly-G Poly-C issues and Adapter Trimming
tails poly-c poly-g adapters
updated by GenoMax 16K • | written by Jon 3
1 vote
1 reply
172 views
News: Machine Learning for Evolutionary Genomics (MLEG01)
machine-learning genomics
updated by Ram 4.5K • | written by oliverhooker 14
0 votes
0 replies
178 views
Job: Resident Academic Full-Time Post in Bioinformatics (University of Malta)
bioinformatics academia
written by jp 13
0 votes
4 replies
296 views
VCF sample id format for snpgdsVCF2GDS (SNPRelate package)
gds snprelate vcf
updated by Arup Ghosh 402 • | written by shpak.max 8
1 vote
1 reply
253 views
Permutation test for convergent gene expression changes
rna-seq randomization permutation
updated by kalavattam 85 • | written by Iulia 1
0 votes
3 replies
523 views
Problems with biomaRt installation due to dplyr function "filter_out"
biomart dplyr bioconductor
updated by Arup Ghosh 402 • | written by shpak.max 8
0 votes
2 replies
291 views
How to find a list of all proteins involved in Alternative splicing regulation
alternative-splicing
updated by GenoMax 16K • | written by mohammad.naweed 0
2 votes
2 replies
231 views
Which key should I use with Harmony?
single cell harmony. rna sequencing
updated by opticlabsau.com 0 • | written by bioinfo 19
2 votes
6 replies
525 views
Looking for help with molecular dynamics simulation of EEF1A2 D91N variant vs wild-type
protein eef1a2 simulation
updated by Michael Dondrup 5.6K • | written by fossy217 2
0 votes
0 replies
96 views
Running pySCENIC for disease vs. control comparison with isoform-level TF dysfunction
single-cell scenic pyscenic
written by qoop59 0
0 votes
5 replies
357 views
assemble_polyg_meta_v1.sh is removing most of my reads
bbmerge ecco shotgun polyfilter
written by GallopingAvocado 3
0 votes
7 replies
560 views
Tool: I made an app that makes DNA files 40% smaller than CRAM , Spring
bam
updated by GenoMax 16K • | written by Dan 0
1 vote
0 replies
87 views
Tool: VizModules: Flexible, Interactive R shiny Modules for Almost Any Plot
shiny visualization plotly r
written by jared.andrews07 1.9K
2 votes
2 replies
247 views
Differential Expression Contrast Interpretation
differential dea contrasts drugs limma
updated by kalavattam 85 • | written by fnepo 4
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