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2 votes
4 replies
987 views
Can a dot (.) be used as the ALT field for a deletion in a VCF file?
vcf deletion ngs
written by terdon 48
0 votes
2 replies
739 views
GATK CalculateContamination (paired mode) - NaN value
gatk calculatecontamination mutect2
written by Livia 0
0 votes
3 replies
784 views
non human homology detection
homology uniprot id
updated by GenoMax 16K • | written by zizigolu 438
0 votes
1 reply
532 views
StringTie to DESeq2 workflow
stringtie deseq2 rna-seq
updated by i.sudbery 2.3K • | written by khanald2114 0
0 votes
5 replies
1.1K views
PacBio HiFi alignment: am I doing this right?
assembly pacbio
updated by Ram 4.5K • | written by matvergara19 0
1 vote
8 replies
13K views
No result in enrichGO
r clusterprofiler enrichgo
updated by GenoMax 16K • | written by sugus 15
0 votes
2 replies
806 views
Using delly to genotype a particular deletion
deletion delly genotyping
updated by trausch 202 • | written by arsala521 6
0 votes
1 reply
930 views
Does it make sense to add together the concentrations of different stereospecifically numbered lipids?
metabolomics lipidomics lipids mass-spectrometry
updated by Ram 4.5K • | written by Katia 0
0 votes
3 replies
1.2K views
How to combine vector fields with Waddington landscapes (utilizing the directional information of RNA velocity for weak constraints)
landscapes cell-fate waddington vector-fields rna-velocity
updated by Ram 4.5K • | written by 167966742 0
1 vote
6 replies
1.1K views
Tool: MirAge - A novel Matrix Analyzer for fast DNA classification
dna analysing tool
written by Maarten Pater 2
1 vote
2 replies
640 views
Clarification on counting in featureCounts
featurecounts
written by Lc 1
0 votes
1 reply
1.1K views
Runtime expectations and alternatives for vsearch --usearch_global on large nucleotide FASTA datasets
ngs performance vsearch sequence-alignment immune-repertoire
updated by dthorbur 350 • | written by emmzee 0
0 votes
1 reply
642 views
Custom background gene set for enrichment in variant-based analysis?
clusterprofiler enrichment pathway analysis
updated by dthorbur 350 • | written by iamsmor 0
5 votes
5 replies
2.8K views
Forum: Forum:What Are The Most Influential Bioinformatics/Computational Biology Papers Of 2025?
bioinformatics genomics survey snps papers
updated by colindaven 844 • | written by Raony Guimarães 153
1 vote
0 replies
510 views
News: Starting the New Year by building the foundations of Data Analysis!
r python statistics programming
written by Physalia-courses 281
0 votes
0 replies
319 views
Cell-type deconvolution before or after ComBat in methylation EWAS?
methylation limma ewas combat deconvolution
written by Eliveri 35
0 votes
2 replies
681 views
Worrisome dispersion plot interpretation (DESeq2)
plot deseq2 deseq2 dispersion
written by IrK 10
0 votes
0 replies
456 views
News: Workshop: Virtual Variant Detection, January 27–29, 2026
uconn bioinformatics genomics workshop variantdetection
written by zsc25001 1
2 votes
1 reply
943 views
Is it expected for T cells to be broadly distributed across the UMAP in pancreatic cancer scRNA-seq data?
annotation single_cell_rna_seq umap scrna-seq
updated by yura.grabovska 94 • | written by Bum 2
1 vote
0 replies
542 views
News: Introductory NGS data analysis & variant calling workshops (online and in-person, early 2026)
sam mapping fastq variants vcf
written by ecSeq Bioinformatics 9
5 votes
9 replies
52K views
Merging/Concatenating Vcf Files
vcftools snp indel
updated by xosiy87829 0 • | written by bioinfo 84
1 vote
4 replies
855 views
Tool: Viral Vector Analyzer - Free Web Tool for AAV/Lentivirus/Adenovirus Analysis
gene-therapy viral-vectors
written by Graham 1
0 votes
2 replies
824 views
News: Developing Shiny Apps with AI - online course in February
r shiny genomics ai
written by Physalia-courses 281
1 vote
1 reply
613 views
Gene Fusion Prioritization Tool
gene vus fusions variants
updated by bioruffo 6 • | written by anuthyagatur 1
0 votes
2 replies
11K views
Any alternative way to do ASAP (Assemble Species by Automatic Partitioning)?
delimitation species test
updated by Paul 0 • | written by Chatchapon 0
0 votes
0 replies
609 views
News: Unlock Deep Learning Skills with Live Online Training in Python and R
python learning deep
updated by GenoMax 16K • | written by oliverhooker 14
0 votes
7 replies
1.4K views
Forum: Is a cross-species scRNA-seq analysis publishable as a hypothesis-generating study without wet-lab validation?
scrnaseq transcriptomics
written by Kurayi Chawatama 0
0 votes
1 reply
470 views
WGCNA basic queries
wgcna
updated by andres.firrincieli 412 • | written by NEWBIE 0
0 votes
2 replies
554 views
Metabat2 Segmentation fault
segmentationfault metabat2
written by Edson 2
0 votes
1 reply
526 views
Large GEO dataset download
dnam geo
updated by GenoMax 16K • | written by jh1997 0
0 votes
1 reply
627 views
R Package PopGenome Will Not Read in Tab indexed VCF file using ReadVCF
r vcf popgenome
updated by GenoMax 16K • | written by owjepson 0
1 vote
0 replies
515 views
Job: Computational Biologist position at the University of Alabama at Birmingham
hiring spatial transcriptomics single-cell rna
written by lianov 4
1 vote
0 replies
593 views
News: A Complete PYTHON Training Pathway for Biologists, Ecologists and Data-Driven Researchers
python
updated by GenoMax 16K • | written by oliverhooker 14
2 votes
2 replies
3.9K views
EggNOG-mapper problem
eggnog
updated by SomeOne 33 • | written by Salma 2
0 votes
7 replies
1.3K views
Braker3 ETP annotations Filtering
braker3 annotations fungi
written by SomeOne 33
0 votes
0 replies
412 views
News: GWAS course - online 18-22 May
imputation gwas r plink
written by Physalia-courses 281
0 votes
2 replies
980 views
Looking for bulk RNA-seq deconvolution papers
rna-seq bulk rnaseq deconvolution python
updated by coolmattmonkey 3 • | written by AlexStar 22
0 votes
1 reply
667 views
GATK Mutect2
gatk mutect2 snp variant-calling
updated by Ram 4.5K • | written by sk_24 0
0 votes
9 replies
1.6K views
Incompatibilities between GATK FastaAlternateReferenceMaker and agat_sp_extract_sequences.pl?
fastaalternatereferencemaker gatk agat
updated by samuel.a.odonnell 86 • | written by nmbaran 2
0 votes
1 reply
462 views
tensorQTL AssertionError
tensorqtl eqtl meqtl
updated by Jeremy Leipzig 2.3K • | written by titangerd 0
1 vote
1 reply
525 views
miRNA Analysis
mirna geneexpression rnaseq mirnaanalysis
updated by GenoMax 16K • | written by Pritesh 1
0 votes
3 replies
938 views
RNA splicing analysis
rna-seq splicing
updated by i.sudbery 2.3K • | written by shafi98 0
0 votes
0 replies
459 views
Forum: Bioinformatics opportunities in Germany
job search germany bioinformatics
written by eyaggelia146 3
0 votes
0 replies
396 views
News: Unix and Shell Scripting for Bioinformatics course - online, 12-16 January
shell conda unix scripting bash
written by Physalia-courses 281
0 votes
1 reply
605 views
Using blacklist in sarek pipeline
sarek tmb
updated by Pierre Lindenbaum 17K • | written by giacomo.bregni 0
1 vote
2 replies
880 views
Handling extra contigs after long-read bacterial genome assembly
nanopore busco plasmids genome-assembly bacterial-genomes
updated by samuel.a.odonnell 86 • | written by Paulina 1
0 votes
1 reply
466 views
Building a hidden markov model from synthetic protein designs
structural-designs msa hmm proteins
updated by Joe 2.2K • | written by v.berriosfarias 14
0 votes
2 replies
868 views
Bioinformatics python
python
written by ogunjinmirashidat 0
0 votes
6 replies
1.7K views
Exclude from analyzing rna-seq samples
rna-seq
written by dropswater 0
1 vote
1 reply
728 views
Running psiblast on AWS with ElasticBlast
psiblast blast
updated by GenoMax 16K • | written by Joshua 1
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