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Forum: I’m considering a career transition from software engineering to bioinformatics. Is it a good fit for me?
career
updated 4 months ago by 142k • written 4 months ago by ▴ 10
9
votes
11
replies
3.3k
views
7 follow
Forum: Fields with biggest demand for bioinformatics?
career
updated 12 months ago by 44k • written 5.3 years ago by ▴ 200
38
votes
17
replies
3.3k
views
7 follow
Forum: Why does bioinformatics use a special format like a BAM file instead of a database like SQLite?
sam bam samtools
updated 11 months ago by 44k • written 3.8 years ago by ▴ 250
10
votes
8
replies
3.1k
views
6 follow
Forum: Cancer research for computer science student
cancer research computer-science
updated 7 months ago by • 0 • written 6.5 years ago by ▴ 70
2
votes
6
replies
3.1k
views
Forum: RIP CentOS, CentOS 8 to be EOL'd in 2021
centos linux-distro os
updated 11 months ago by 44k • written 3.5 years ago by 11k
64
votes
24
replies
3.1k
views
12 follow
Forum: How much I must feel useless?
machine-learning Programming statistics
updated 12 months ago by 44k • written 5.6 years ago by ▴ 80
12
votes
12
replies
3.0k
views
Forum: Programming interview via Skype
programming-test interview
updated 12 months ago by 44k • written 5.9 years ago by ▴ 50
34
votes
22
replies
3.0k
views
11 follow
Forum: Have we failed as bioinformatician in this time of COVID-19
Bioinformatician COVID-19
updated 11 months ago by 44k • written 4.0 years ago by ▴ 10
0
votes
1
reply
3.0k
views
Forum: Bioinformatics Master thesis
thesis
updated 12 months ago by 44k • written 5.4 years ago by ▴ 20
12
votes
2
replies
3.0k
views
Forum: List of genome annotation tools (>140)
gene genome
updated 11 months ago by 44k • written 4.8 years ago by 8.6k
4
votes
6
replies
2.9k
views
Forum: NGS Data Storage Best Practices (Clinical)
NGS clinical storage
updated 11 months ago by 44k • written 4.4 years ago by ▴ 630
8
votes
6
replies
2.9k
views
Forum: Demonstrating Exponential Growth In Pre-School
education
written 10.3 years ago by 10k
3
votes
4
replies
2.8k
views
Forum: hands on resources for high school students with advanced CS skills
informatics education high-school
updated 12 months ago by 44k • written 5.8 years ago by 4.2k
1
vote
13
replies
2.8k
views
Forum: Bioinformatics computer upgrade help
computer
updated 11 months ago by 44k • written 3.9 years ago by ▴ 50
7
votes
6
replies
2.8k
views
7 follow
Forum: Should I specialise in bioinformatics?
career
updated 12 months ago by 44k • written 5.6 years ago by ▴ 10
31
votes
41
replies
2.8k
views
12 follow
Forum: Question regarding journal publications
publications journals
updated 11 months ago by 44k • written 4.2 years ago by ▴ 40
29
votes
18
replies
2.8k
views
12 follow
Forum: what are the big questions in bioinformatics field nowadays
genome
updated 11 months ago by 44k • written 4.2 years ago by ▴ 20
34
votes
8
replies
2.7k
views
9 follow
Forum: Bioinformatician, a jack of all trades, but in the eye of the CV-beholder a master of none? How can your CV reflect the diverse skills that you have …
cv industry career
updated 11 months ago by 44k • written 4.6 years ago by ▴ 300
3
votes
27
replies
2.6k
views
7 follow
Forum: What server do you use?
HPC AWS
updated 12 months ago by 44k • written 5.9 years ago by ★ 1.9k
12
votes
5
replies
2.6k
views
Forum: We Need Your Input! Help Get Information For The Informatics Community And Get A Free Gift Card!
algorithm ngs
updated 11 months ago by 44k • written 11.0 years ago by ▴ 30
21
votes
11
replies
2.6k
views
6 follow
Forum: Rust bioinformatics projects ideas
projects scRNA-seq RNA-seq Rust
updated 6 months ago by 22k • written 14 months ago by ▴ 150
14
votes
6
replies
2.6k
views
6 follow
Forum: Bioinformatics experience in programming
python R
updated 12 months ago by 44k • written 5.7 years ago by ▴ 20
18
votes
12
replies
2.5k
views
6 follow
Forum: why GATK makes things more complicated ?
genomics
updated 12 months ago by 44k • written 5.3 years ago by ▴ 280
12
votes
14
replies
2.5k
views
8 follow
Forum: Recovering bam files after unknown deletion in the storage
photorec bam sequencing
written 4.9 years ago by ▴ 70
6
votes
4
replies
2.5k
views
Forum: Ru/Read Until in Nanopore sequencers
Oxford-Nanopore alignment sequencing
updated 11 months ago by 44k • written 4.3 years ago by ★ 1.7k
18
votes
11
replies
2.5k
views
8 follow
Forum: Create a File format to store Variant
hgvs json variant
updated 12 months ago by 44k • written 5.9 years ago by ★ 2.4k
5
votes
5
replies
2.4k
views
Forum: BCL files as deliverables from a sequencing center
core-facility service-provider
updated 11 months ago by 44k • written 5.0 years ago by 5.2k
7
votes
8
replies
2.4k
views
Forum: Virus Genome Length and GC Content of SARS-COV-2 causing COVID-19
sequence genome
updated 11 months ago by 44k • written 4.2 years ago by ▴ 30
15
votes
10
replies
2.4k
views
6 follow
Forum: help identifying bioinformatics operations tools
database next-gen operations genomics
updated 12 months ago by 44k • written 5.5 years ago by ▴ 80
6
votes
5
replies
2.3k
views
Forum: Maintaning internal or private installation of Biostar or a similar Q&A site
Biostars
6 months ago by tshtatland ▴ 190
10
votes
7
replies
2.3k
views
Forum: How to learn bioinformatics?
learning
updated 4 months ago by ★ 1.3k • written 2.0 years ago by ▴ 20
28
votes
15
replies
2.3k
views
12 follow
Forum: Should bioinformaticians learn the scientific names of plants and animals?
sequence
updated 12 months ago by 44k • written 5.9 years ago by ▴ 10
30
votes
16
replies
2.3k
views
9 follow
Forum: Which programming langauge shall I start as a beginner in Bioinformatics
programming-language single-cell
updated 11 months ago by 44k • written 4.1 years ago by • 0
19
votes
15
replies
2.3k
views
Forum: What is the amount of sequencing data produced annually?
data research sequencing
updated 2 days ago by • 0 • written 8 months ago by ▴ 70
6
votes
1
reply
2.3k
views
Forum: How to become employable in Bioinformatics, starting with degree and experience in CS/Software Engineering?
computer-scientist software-engineer
updated 12 months ago by 44k • written 5.8 years ago by • 0
0
votes
4
replies
2.2k
views
Forum: Multiple Sequence Alignment Applications
snp
updated 11 months ago by 44k • written 4.8 years ago by • 0
4
votes
2
replies
2.2k
views
Forum: wet-lab vs dry-lab scientists
cv language
updated 11 months ago by 44k • written 4.3 years ago by 13k
0
votes
1
reply
2.2k
views
Forum: How's the bioinformatics engineering path? How to become a bioinformatics engineer?
machine-learning Bioinformatics-engineer
updated 11 months ago by 44k • written 4.0 years ago by ▴ 70
10
votes
6
replies
2.2k
views
Forum: How to acknowledge in the paper a reference genome that hasn't been published yet?
reference paper
updated 12 months ago by 44k • written 5.8 years ago by ▴ 140
26
votes
27
replies
2.2k
views
10 follow
Forum: Determining computer time required
computer hpc time
updated 4 months ago by ★ 6.1k • written 4 months ago by ▴ 40
31
votes
16
replies
2.2k
views
8 follow
Forum: What is in your opinion the current state-of-the-art sequencing platform for genomic assembly (Nov 2019)
next-gen-sequencing assembly genome
updated 11 months ago by 44k • written 4.6 years ago by ★ 5.1k
7
votes
7
replies
2.2k
views
Forum: Bioinformatician who was retaliated against after reporting discriminatory harassment - Please help me navigate getting out of the situation I'm in
Career advice
updated 5 weeks ago by ★ 2.5k • written 5 weeks ago by • 0
10
votes
15
replies
2.2k
views
Forum: How should reference genome fasta files be distributed by UCSC?
reference-genome fasta freeze ucsc-genome-browser
updated 11 months ago by 22k • written 15 months ago by ★ 1.6k
14
votes
10
replies
2.2k
views
Forum: WGBS alignment with BitMapperBS
BitMapperBS bismark
updated 11 months ago by 44k • written 4.9 years ago by ★ 9.4k
3
votes
6
replies
2.2k
views
Forum: Choosing the appropriate test for differential analysis: Limma or Mann-Whitney (with BH correction)? Test for normality
R Shapiro-Wilk Limma Mann-Whitney
updated 11 months ago by 44k • written 4.0 years ago by ▴ 40
3
votes
14
replies
2.2k
views
6 follow
Forum: Search for gene variants
next-gen
updated 12 months ago by 44k • written 5.8 years ago by 8.3k
49
votes
20
replies
2.1k
views
10 follow
Forum: First experiences matter
first-time tolerance
updated 4 months ago by ★ 2.6k • written 4 months ago by ★ 27k
16
votes
8
replies
2.1k
views
8 follow
Forum: What are the most important unresolved problems in Bioinformatics?
bioinformatics
updated 10 months ago by 44k • written 7.6 years ago by ★ 2.5k
21
votes
15
replies
2.1k
views
9 follow
Forum: Working abroad without a PhD
career
updated 11 months ago by 44k • written 4.7 years ago by ★ 1.4k
23
votes
11
replies
2.1k
views
9 follow
Forum: file and directory management best practices
file-management
updated 11 months ago by 44k • written 3.8 years ago by ▴ 140
319 results • Page 2 of 7
Recent Votes
A: Fold change - a final explanation
Comment: scRNA-seq quality control
Comment: How to get the ratio of allele counts from GATK derived VCF file?
Setting up Aspera Connect (ascp) on Linux and macOS
Setting up Aspera Connect (ascp) on Linux and macOS
Answer: Genes' fpkm values through cufflink
Answer: Genes' fpkm values through cufflink
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Recent Awards • All
Scholar to LChart 3.9k
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Recent Replies
Comment: Is it possible to run CibersortX with a very small number of samples? by Aspire ▴ 330
Thanks. I have checked that all files are tab delimited, with the first column named Gene_Symbols, with capitalized gene symbols, and no qu…
Answer: samtools write-index by aw7 ▴ 300
Someone, presumably you, opened an [issue][1] for the same problem. The answer was: > This problem should be fixed in htslib 1.20 (incl…
Answer: How do we do quantification using stringtie merge option for all the merged samp by i.sudbery 19k
If you are asking StringTie to estimate expression, then you need to provide it with BAM or CRAM files of the original reads, not a stringt…
Answer: How to interpret this plotMDS of three disease clusters? by i.sudbery 19k
> 1) How should I interpret this, can I say that there are practically no differences or outliers? You can say that the inter-group vari…
Comment: Ideal PC configurations and operating system for bioinformatics laboratory by emmanouil.a ▴ 120
personaly I see the workstations in long-term ... maybe today you are running only scRNA but having a good workstation tomorrow you can als…
Comment: Z score by Akash D ▴ 40
Alright! Got you...
Comment: Ideal PC configurations and operating system for bioinformatics laboratory by i.sudbery 19k
It very much depends on whether the OP does want/need to do the CellRanger runs locally or not. Doesn't really matter if its only occasion…
Comment: log2 fold change in RNA-seq analysis by Mensur Dlakic ★ 27k
Everything is already explained on this page, just read everything already written above. Specifically, [**this comment**][1]. [1]: htt…
Comment: log2 fold change in RNA-seq analysis by May Ling • 0
Good day everyone, Sorry I found a bit confusing and would appreciate if I could clarify on the calculation. I am using DESeq. My desire…
Answer: GWAS Phenotypes by 韩雨 • 0
In my opinion, the basis of the question is to solve whether the phenotype is regulated by genetics. In the aspect of genetic, the estima…
Answer: Classic threshold for log2 fold change in RNA-seq experiment by May Ling • 0
Good day everyone, Sorry I found a bit confusing and would appreciate if I could clarify on the calculation. I am using DESeq. My desire…
Comment: some error in building kraken2 database by ahmet • 0
Were you able to fix this issue? I'm also trying to add external species to krakendb
Comment: Z score by ATpoint 82k
logFCs are a bit difficult to cluster I think, because fold changes without stats attached to it are meaningless. They can be very big, due…
Comment: Z score by Akash D ▴ 40
Ok. However, if i perform it on log2FC, there wont be any control samples visible in my heatmap. Your answer is perfect.
Comment: Z score by ATpoint 82k
You can apply Z-scores on whatever you want, but it must make sense and depends on what you want to do. What is the context? See for exampl…
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