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Nucleotide sequence of an Enzyme

Hi,

I want to download nucleotide sequence of all hydrolases and Isomerases enzyme found in humans. Please suggest me how to download them all at a time.

enzyme nucleotide-sequence protein
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updated by Ram Ram • written by pradeep.pant25 • pradeep.pant25

Thanks for reply, but this will give me amino acid sequence of those 353 sequences and I am asking for nucleic acid sequence.

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written by pradeep.pant25 • pradeep.pant25

3 answers

hi, on uniprotkb you can search for hydrolases and isomerases sequences then you can selected the species in this case human and select all and click on download.

example :

http://www.uniprot.org/uniprot/?query=hydrolases&fil=organism%3A%22Homo+sapiens+%28Human%29+[9606]%22&sort=score

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written by a.polo88 a.polo88

your method will give me amino acid sequence only but not nucleotide sequence of those enzymes and I am looking for nucleotide sequence of enzymes.

thanks anyway.

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written by pradeep.pant25 • pradeep.pant25

search GO for hydrolase: http://amigo.geneontology.org/amigo/term/GO:0016787

download the genes associated to this term: Gene Names From Go Accessions Numbers

then get the sequences: How To Download Gene Sequences From Ncbi Gene

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written by Pierre Lindenbaum Pierre Lindenbaum

it's is true him ask about nucleotide sequences i have seen bad but in this case is not to much simple to use ensembl?

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written by a.polo88 a.polo88

it's is true him ask about nucleotide sequences i have seen bad but in this case is not to much simple to use ensembl?

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written by a.polo88 a.polo88

You can try the following Ensembl biomart query.

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written by Michael Dondrup Michael Dondrup

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