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Mouse RefCDS for dNdScv package

Hi all

I am trying to run the dNdScv package to identify mutations that are under positive selection. The dataset I am working with is sequencing data from mouse tumours using a targeted gene panel.

The default for the package is using human data. Does anyone have a RefCDS object already for mouse (mus musculus) that I can use to apply the algorithm to my data?

Here is the page for the package: dNdScv

Thank you!

musculus dndscv mus refcds mouse

1 answer

Hello

Thank you for your interest in dNdScv. You can find a number of RefCDS for other species, including mouse, in this link: https://github.com/im3sanger/dndscv_data/tree/master/data

You can also use this tutorial to generate your own RefCDS for any species or transcript dataset of interest.

Best, Inigo

Thank you Inigo, and thank you for all your work with this package!

Best wishes.

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