Is there any book about it?
I am looking for the text about introduction to NGS data analysis and its challenges. Is there any suitable literature (book or review article) on statistical challenges for analyzying NGS data?
3 answers
Check the tutorial section for a head start.
Few posts:
- Challenges and Solutions in the Analysis of Next Generation Sequence Data
- Tutorial: Workshop - Analysis of Next Generation Sequencing Data
- Tutorial: High Throughput Sequence Analysis with R and Bioconductor
- Tutorial: Introduction to NGS Bioinformatics by the Bioinformatics Team at the University of Texas
- Open wikiBook Next Generation Sequencing (NGS)
The field is moving too fast for any book to be relevant for too long. The best you can do is maybe check books on microarray analysis.
There's also an excellent seminar series on iTunesU that covers a wide range of NGS topics - very appropriate for NGS newbies, grad students, etc. - sponsored by the Smithsonian Institution
Smithsonian Institution National Museum of Natural History - Next Gen Sequencing https://itunes.apple.com/us/itunes-u/next-gen-sequencing/id419187633?mt=10
There's also George Church's lectures on NGS and genomics at the MIT Open University https://itunes.apple.com/us/itunes-u/genomics-computational-biology/id341598226?mt=10
My be this not what you are looking for, but this might be helpful http://www.csc.fi/english/csc/courses/archive/ngs_workshop
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