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Comparing Assembler Outputs With Respect Of Indels & Substitution Errors

I've the results of two assemblers (multiple FASTA files for each assembler, and each one represents a contig). I also have a reference genome.

I want to compare the results of each assembler in terms of indel and substitution error. How can I do that?

Thank you

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2 answers

Mauve Assembly Metrics might help you:

http://bioinformatics.oxfordjournals.org/content/early/2011/08/02/bioinformatics.btr451.abstract

http://ngopt.googlecode.com

The software GAGE was designed specifically for evaluating differences in assembly metrics and error rates between assemblies.

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