Best way to deal with chimeric reads? · Biostar

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Best way to deal with chimeric reads?

Hi everyone! I have some DNA data (custom panel on human gene) that have a lot of chimeras reads, due to the library preparation procotol. I have aligned the data with BWA and then call variants with GATK HC, but I was wondering if there is a better way to align the chimeric reads and call variants on them. Thanks

sequencing alignment illumina short-reads chimera

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written 5.7 years ago by deniselavezzari •

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