calculate the minimum free energy of RNA structures
I need some help to calculate the minimum free energy of RNA structures from RNA sequences. I have a list of 5000 or so RNA for which I need to calculate the minimum free energy. I have the FASTA file for the same. I was trying to use web-based interface ViennaRNA Web Services, but it calculates only one sequence at a time. Are you guys aware of any package in R to calculate the same? I will appreciate the help.
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Can't you install and run ViennaRNA locally?
As easy as:
conda install -c bioconda viennarna