I am working on the RNAseq samples. Planning to do pathway analysis and gene enrichment analysis. As of now don't have much background on these analyses. Currently doing some background research. If you people know some useful resources, kindly do share with me.
- At first instance, why do we do pathway analysis and gene enrichment analysis?
- Have a set of genes which are upregulated and down regulated between wild type and mutant, how to get enrichment score for upregulated genes and down regulated genes?
- How to identify which pathways are enriched in the wild type and mutant samples?
- How to identify which pathways are enriched in upregulated or downregulated genes?