How to identify the pathways that are enriched in up-regulated and downregulated genes from RNAseq?
Hi friends,
Which approach is correct to do GSEA and pathway analyses.
- considering all ~20,000 genes as the input for Broad's GSEA tool
or
- considering only the significantly (p.adj < 0.05) differentially expressed genes as the input for Broad's GSEA tool
My aim is to identify the pathways that are enriched in up-regulated and down-regulated genes.
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