Gibbs free energy for 260,000 different short RNA duplexes (11nt)
Hi,
for my project, I would like to check for 260,000 sequences, how big the Gibbs free energy for the formation of an RNA dublex with one single RNA strang would be. I didn't find a way to do this with the mfold programm and couldn't find anything with google.
All sequences are 11 nucleotides long and only consit of A, U, G and C.
Do you maybe know a programm or general way, how to calculate the Gibbs free energy for all the different duplexes?
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