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What tools can be used for analysis of structural variants in targeted sequencing data?

What are possible tools that can be used for analysis of structural variants and easy to interpret in targeted sequencing data approach without providing control samples (Human samples) ?

Thank you.

snp cnv snv targeted sequencing ngs
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updated by Sparrow_kop Sparrow_kop • written by mittu1602 mittu1602

pindel might be worth a look, though I don't know how well it works for targeted sequencing data. Think it's meant more for whole genome analysis.

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written by jared.andrews07 jared.andrews07

1 answer

Hi, I recently also conduct the SV analysis of target sequencing. From my own experience, I think you can try manta, a very sensitive and high performance tool which also under active maintain. Also It can analysis single sample without control sample, you can refer the manual.

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written by Sparrow_kop Sparrow_kop

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