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Big Data tools for Bioinformatics

What are the Big Data tools in Bioinformatics?

I found one project using ADAM:

bdgenomics.org

big data spark hadoop

Given how ill defined it is what constitutes "big data" and thus "big data tools", I don't think there is a good answer to this. Are NGS data big data? Are bioinformatics tools for analysis of NGS big data tools? Is R a big data tool? Are NoSQL databases big data tools?

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