Yes, for my research it was the best, and also it has the last update upon all others databases.
Hi Everybody,
Somebody knows which is the most complete and updated database for looking miRNA gene-targets (validated targets)? I have tried miRWalk but some results makes me think that is incomplete or outdated. I have hundreds of miRNAs to assign function so I need that the data looks like GSEA files on miRwalk.
Thanks!
5 answers
Highly recommend miRTarBase - provides a variety of filtering options including validation status.
You can try the starBase (http://starbase.sysu.edu.cn/) database, it has been updated to decode miRNA-mRNA, miRNA-lncRNA, miRNA-sncRNA, miRNA-circRNA, miRNA-pseudogene, protein-lncRNA inteactions from CLIP-Seq (HITS-CLIP, PAR-CLIP, iCLIP, CLASH) and degradome sequencing data.
starBase also decipher Pan-Cancer Analysis Networks of lncRNAs, miRNAs, ceRNAs and RNA-binding proteins (RBPs) by mining clinical and expression profiles of 14 cancer types (>6000 samples) from The Cancer Genome Atlas (TCGA) Data Portal.
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You are looking for miRNA-mRNA pairs validated using experimental data? I expect that set to be rather limited.
Yes, it is, but target prediction is even worst and limited I think so.