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Are there any new/novel R packages and other software to compare a 100 of VCF files?

Are there any new/novel R packages and other software to compare a 100 of VCF files? Tried GATK and VCF tools and nextGene. Need a better solution for a hunderds of VCFs.

vcf r

Could you be more specific on what you aim to achieve? "Compare" is quite generic.

Oh right now I understand. Differences.

Could you be more specific on what you aim to achieve? "Differences" is quite generic.

Not new and not sure whether it fits your needs but did you take a look at the VariantAnnotation bioconductor package?

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