I have the mouse genome split into 1000 bp bins. For each bin, I'd like to know how far is it from the nearest gene. A question I posted yesterday got the answer of using biomart (and its R package biomaRt). Going through biomart, I am a bit confused about the GO ontology terms: Consider the following diagram:
Consider a particular gene, with a particular transcript:
Why would a particular protein have so many GO terms? I am a math major and never really got introduced to GO ontology so if someone could explain this to me? I understand the terms as they are defined on http://geneontology.org/page/ontology-documentation but I am not sure why a particular protein would require so many terms.
Hello Affan
Here's the description Go Terms -- Is It Normal To Have Multiple Go Terms Associated With A Specific Gene/Locus?
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written
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Dr Reema Singh
Good find, figures that I've answered a question like this before. In particular, the answer from justinhaselbach is useful, since it emphasizes the fact that a single gene can produce proteins with multiple functions, locations, and modes of action in different (or even the same) contexts.
As far as I can see your screen show all the ancestors of only a few GO term : e.g: cytoplasm is_part_of_a cell is_a cellular_component
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written
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Pierre Lindenbaum
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