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Trying to Understand why and how NGS Reads follow Poisson Distribution

I am reading the basic concepts in NGS alignment and mapping and I understand the Poisson distribution characteristics of the short random reads generated by the sequencer machines are the key in designing these mapping algorithms either sequence wise or word matching methods.

Can someone explain and help me understand how the NGS reads follow poisson distribution?

statistics alignment next-gen poisson-distribution
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updated by Ram Ram • written by vigprasud vigprasud

You should try to phrase your question more precisely. The answer to your literal question is: "NGS reads do not follow a Poisson Distribution" The distribution defined for counts of events not for the reads itself.

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updated by Ram Ram • written by Michael Dondrup Michael Dondrup

1 answer

Hello vigprasud!

Questions similar to yours can already be found at:

We have closed your question to allow us to keep similar content in the same thread.

f you disagree with this please tell us why in a reply below. We'll be happy to talk about it.

Cheers!

PS: Thanks pois(s)onAlien ;)

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updated by Ram Ram • written by Michael Dondrup Michael Dondrup

Thank you guys. Shall follow the other thread.

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updated by Ram Ram • written by vigprasud vigprasud

Haha.. I see what you did there :D

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updated by Ram Ram • written by poisonAlien poisonAlien

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