Program For Retreiving Refseq Sequence

Question

[Divya]

Hi,
Thanks in advance.I have to download the entire refseq files from NCBI.Is there any way to write a program for downloading these files ?

Answer 1

[Pierre Lindenbaum]

If you're familiar with unix, have a look at those FTP/HTTP clients

• curl : http://curl.haxx.se/
• wget http://www.gnu.org/software/wget
• ....

as your question is not strictly related to bioinformatics (it could be any kind of file), you can also submit your problem at http://superuser.com/

[Giovanni M Dall'Olio]

wget -r ftp://ftp.ncbi.nih.gov/refseq/release -w 1

this will download the whole latest refseq release on the current directory, recursively. The -w option is recommended because it will lightens the load on ncbi's server.

[User 59]

Anything that can recursively handle an FTP connection would do, including most FTP clients...

Answer 2

[Giovanni M Dall'Olio]

wget and curl are very good options. If you want something more user-friendly, DownloadThemAll is a nice Firefox extension.