LD store2 cannot be matched
I used the IEU Open GWAS to generate Z file, BGEN file, and BGI file in order to create an LD matrix for FINEMAP. I am a beginner in the field of bioinformatics. I have tried various ways, but I still failed. I sincerely want to know where the problem is.
this is vcf I use ,I selected the positions around lead SNPs within a 500 kb range.
this is Z file.
this is begn file.
this is the problem I am facing on.
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You can use qctool to output snpstat files and you will have the A1/A2 column, use those to link back to your .z file : )
The question I want to ask is why bgen file can not be matched with z file. If I use qctools, this question will be resolved?
It seems ldstore2 require strict agreement between z and bgen, I usually do that with qctools and haven't failed so far : )