Merge different vcf files
Hi, I have some vcf files in which some ref alleles are different for the same region. Can I merge all vcf files or do I have to standardize these ref alleles?
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caique.manochio •
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Normalize them first using
vt normalizeorbcftools norm- they need to be in left-aligned parsimonious representation before you can do an accurate merge if required.Thank you!