Multiple SRR files correspond to the same GSM in GEO

If there are multiple SRR files correspond to the same GSM in GEO database (GSE178366) as bellow enter image description here

How should I process it before mapping ?(merge these two fastq files?)

Thank you

fastq geo

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written 1.9 years ago by SHIRUI •

1 answer

I'd look carefully at the GSM record for this. But the most likely explaination is that the same sample was run on different lanes to generate enough sequence. If thats the case then you can merge the fastqs before starting your analysis.

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written 1.9 years ago by i.sudbery

OK got it thank so much

I can use "cat" merge them directly right?

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written 1.9 years ago by SHIRUI •

Yes you can merge two gzip compressed files by the same command..

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written 1.9 years ago by GenoMax

OK thank you so much

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written 1.9 years ago by SHIRUI •

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