Is it reasonable to do "Gene Regulatory Network Inference" for each cell type and do differential GRN
Hi, everyone.
I want to compare the influence of drug or something else for different cell type. I have a idea. First, I will do GRN(Gene Regulatory Network) for each cell type. Then I will do differential GRN for paired cell type between treatment and control.
I just wondering whether it is reasonable or there are some papers describling these ideas.
Thanks for your viewing :)
Best wishes
Guandong Shang
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shangguandong1996 •
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shangguandong1996 •
1 answer
Sure. In one of our preprints, we did sort of a similar thing on cells from different time points.
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