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Pathway Enrichment Analysis according to tumor mutation burden.

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Hi, I wanna enrich associated pathway according to the value of tumor mutation burden on R, just like this figure from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235024/, and I cannot find out a certain way to do so, any suggest is great!

tmb tcga r maftools

1 answer

You could use clusterprofiler to run an over-representation test in R.

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