Imputation during SNPs calling

Hi,

Why we do imputation analysis during SNPs analysis. I am am not exactly sure what it means and how it helps in SNPs analysis. I only understand that Imputation SNPs only present in reference panel so why do we need them during genotyping?

Many thanks, nabiyogesh

genomics statistics bioconducter

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written 4.2 years ago by Bioinfonext

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