This is a test version of Biostars. For the public version, visit https://www.biostars.org.
New Human genome FASTA

Hi!

How do we access the newly published complete human sequence. (https://www.science.org/doi/10.1126/science.abj6987)

Is GRCh38.p14 the new complete version of genome?

Thanks!!

referencegenome
• 2,087 views • link
updated by GenoMax GenoMax • written by Raman2 • Raman2

1 answer

You can find CHM13 T2T assembly here (LINK for NCBI page) and direct LINK for sequence. I don't think it is appropriate to call it GRCh38.p14. Since this sequence is from a specific cell line I doubt it will get that patch name. In any case GENCODE is the official organization that releases site is where you will find authoritative human genome builds.

• 0 views • link
written by GenoMax GenoMax

Thank you GenoMax! Can we use this as the new reference genome or should we still be using the existing gencode genome (GRCh38.p14)

• 0 views • link
written by Raman2 • Raman2

For continuity and compatibility with existing annotation current GENCODE genome would still be the safe bet.

• 0 views • link
written by GenoMax GenoMax

In any case GENCODE is the official organization that releases authoritative human genome builds.

Genome Reference Consortium is the one that releases GRC genome assemblies such as GRCh38.p14.

• 0 views • link
written by vkkodali_ncbi vkkodali_ncbi

Log in to answer this question.

More posts like this