2 answers
"Suitable" is very context-dependent, are you working with WGS or WES data? short o long reads? Check the Mutect2 pipelines from GATK and you must look for other variant callers in the literature.
https://github.com/nf-core/sarek
Sarek is a workflow designed to detect variants on whole genome or targeted sequencing data. Initially designed for Human, and Mouse, it can work on any species with a reference genome. Sarek can also handle tumour / normal pairs and could include additional relapses.
The pipeline is built using Nextflow, a workflow tool to run tasks across multiple compute infrastructures in a very portable manner. It comes with Docker containers making installation trivial and results highly reproducible.
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