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How to convert a HG19 Hi-C hic file to HG38?

Hi,

I have a Hi-C hic file associated with the HG19 genome. How can I convert it to HG38?
I have looked at Juicer Tools dump, but it looks as though you can only extract data to a sparse format for individual, or pairs of, chromosomes.
Ideally I want to be able to extract the data to a non-binary format, convert it to HG38 (possibly via crossover), then recreate the hic file.

Has anyone done this?

Thank you.

hi-c hic
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updated by Y • Y • written by Ian Ian

1 answer

You can use HiCLift to convert genome assemblies of chromatin concat data (.hic or .cool).

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written by Y • Y

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