This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Reference Genome dna, rm or sm??

I found three types of Toplevel genome i.e dna, rm and sm. By now I know the difference but which to use for your for RNA-Seq analysis?

Any help would be appreciated

Thank you Akash

unmaksed reference masked genome

1 answer

See Why is human genome FASTA file on GENCODE much smaller than that on ENSEMBL?

Use primary unmasked genome. Do not use Toplevel file.

Log in to answer this question.