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Denovo Variation Rate

Respected all,

I need a suggestion from you . I am trying to estimate the denovo variation rate in an model organism. I have the SNP file for both parents and 10 off-springs. But I got stuck how to calculate it. Can anyone please give some suggestion on this?

Thanks

denovo mutation
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updated by Biostar 380 • | written by peris 12

Please make sure not to introduce typos in new tags ('mutationn'), choose existing tags whenever possible.

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written by Michael Dondrup 5.6K

Thanks for your comment. I will be careful in future.

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written by peris 12

1 answer

You can analyze using the Genome Analysis Toolkit

For further information see http://www.nature.com/nature/journal/v488/n7412/full/nature11396.html%3FWT.ec_id=NATURE-20120823

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written by jackuser1979 89

Thanks for your comments.

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written by peris 12

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