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How To Generate A "Lollipop" Image To Display Mutations Along A Sequence

How could I generate a similar visual with the "lollipop" given my own data. Is there any software available out there?

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On the cBioPortal : ( http://www.cbioportal.org/public-portal/index.do?cancer_study_id=luad_tcga&genetic_profile_ids=luad_tcga_gistic&genetic_profile_ids=luad_tcga_mutations&case_set_id=luad_tcga_cnaseq&gene_list=LATS1+LATS2&Action=Submit&tab_index=tab_visualize# ) , under the mutations tab, there is a graph of the number of mutations and mutation rate.

mutation genome cancer

This works wonderfully and it's so simple to install/run. Very similar to mutationMapper, but instead of the hight of the lollipop showing the frequency of the variant, the size of the circle does it. Less easy to see differences but it makes up by the simplicity of running it.

Does this work for mouse data also?

3 answers

Related: how to create mutation diagram in R or in any tools?

See this lollipop generator: https://github.com/pbnjay/lollipops

How do I use it? In command line or bash?

If you're comfortable with R, this works great!

https://bioconductor.org/packages/release/bioc/vignettes/trackViewer/inst/doc/trackViewer.html

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