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List Of Software For Calculating Heritability

I need a list of softwares which can be used to calculate heritability and also would like to know the advantages and disadvantages of each software. Thanks

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updated by Obi Griffith Obi Griffith • written by Omid Omid

Could you define heritability more precisely for us? What type of data do you want to work with?

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written by Matt Shirley Matt Shirley

I have some families with Congenital Hypothyroidism.I have their pedigrees,affected child ,parents and grand parents information.That means three generations.Thanks

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written by Omid Omid

but, you know the gene/variant that causes the disease, or are you trying to define it?

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written by JC JC

we some causative genes but there are also unknown genes which probably cause to disease. Indeed we want to calculate heritability in a population based on pedigrees.

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written by Omid Omid

Different statistical analyses (e.g. regression and hierarchical anova) could estimate the heritability based on the phenotypic trait variance depending on the relationship between individuals (population sampled) and environmental factor. In this case, any statistical software could perform those analyzes, but I always prefer R. For pedigrees see Chapter 27 "Variance-Component Estimation with complex pedigrees" (Linch & Walsh 1998). Cheers, Anselmo.

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written by anselmobiologia • anselmobiologia

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