I'm aware of the gencode annotation, and RefSeq annotation. Those do a good job at providing gene annotations & models, showing where all the known exons / introns are. In practice, these types of annotations often mean presenting for each gene:
a collection of intervals that go together to form a gene, and some sort of meaningful tag/annotation for each of these intervals
Based on recent studies of splicing, what is available out there (supplementary materials / annotation files / databases) that do not only list intervals + annotations for a gene but also show alternative splicing structure? Present all the observed transcripts / isoforms in one annotation?
Thank you!
2 answers
Ensembl is also well populated for human alternative splicing in their own graphic displays
You can look at the example for BACE1 in both
http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?db=human&term=BACE1&submit=Go
There maybe differences though
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