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How to add the amount of conservation (*);(:);(.) to an established multiple sequences alignment?

I would like to add the conservation data to my multiple sequences alignment (i generated it before, but it was saved in FASTA format and i don't have the conservation data; '*': Exact, ':': Conserved Substitution, '.': Semi-conserved substitution). Is there any way to do it? Thank you.

alignment msa conservation
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written by cornflower.9aceeb • cornflower.9aceeb

2 answers

This is not exactly what you are asking for, but still it may be helpful.

http://prodata.swmed.edu/al2co/al2co.php

In one of its several outputs it will print a number above each alignment column, where 9 is absolutely conserved and 0 is completely random. The program can be downloaded here for local use.

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written by Mensur Dlakic Mensur Dlakic

For anyone who has the same question, you can use unipro UGENE to save as the multiple sequence alignment along with the conservation data (as a Clustal file format).

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written by cornflower.9aceeb • cornflower.9aceeb

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