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how to select important / meaningful mutation sites of SARS-CoV-2 ?

I'd like to do a research concerning SARS-CoV-2 mutations. I was wondering, how to select important / meaningful mutations or do I need to analyse / compute mutations by sequences alignment, trimming, and computer analysis softwares? Any comments are greatly appreciated.

rna-seq sequencing
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updated by yjn • yjn • written by 2001linana • 2001linana

The question is too vaguely formulated e.g. mutations important for what? For how to deal with sequence variations, take a look at existing workflows, for example on the Galaxy COVID 19 portal.

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written by Jean-Karim Heriche Jean-Karim Heriche

2001linana : Don't forget to follow up on your threads.

If an answer was helpful, you should upvote it; if the answer resolved your question, you should mark it as accepted. You can accept more than one if they work.
Upvote|Bookmark|Accept

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written by GenoMax GenoMax

1 answer

Maybe you can have a look at GenBrowser(http://www.egps-software.org/ )which provides convenience for analysis of nCOV-19 data. The main functions include evolution tree visualization, genome browser and related data analysis. And our next version will soon pop up online which provides non-neutral evolution analysis function in Stand-alone version.

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updated by GenoMax GenoMax • written by yjn • yjn

Try now. Link corrected above.

2001linana : You have asked a lot of questions here in past few days. That is great but you should follow-up on past threads by validating comments/answers. Participants are all volunteering their time and acknowledging their help is perfect way of showing your appreciation for that help.

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written by GenoMax GenoMax

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