Great Python tool(s) for simulating fake/dummy VCF files?
2 answers
Maybe it is better to simulate fastq files, and create VCF files yourself. This may give a bit more control.
Actually another tool from BBMap suite called mutate.sh will introduce mutations in a reference you provide. You get control over mutation creation. The tool will also create a corresponding VCF file for the mutations it creates. See the inline help for more information.
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