Hello EVeryone, I am a computational biologist, working on standardizing NGS pipelines. I have recently started to RUN qtl-seq pipeline. I have faced many gliches …
I have found this pipeline designed to detect signatures of positive selection from vcf data, but it claims it is only designed for diploid organisms. …
A major QTL on Chr6 was identified using Biparental mapping approach. This QTL was also observed for the same trait in another RIL mapping population …
If you don't have recombination you can't do QTL. There are other methods you can use and the genetics is typically much easier.
thanks for your answer. And for diploid, should we have data from different generations or should we simulate the recombination?
You can use only one generation, what do you mean "simulate the recombination"?
I mean if we do not have the offsprings of the generation, how can we know about the outcome of recombination?
You look at a specific generation, it already went through recombination.