Hello, Ka/Ks ration is the number of nonsynonymous substitutions per nonsynonymous site (Ka) to the number of synonymous substitutions per synonymous site (Ks). I am …

Is there a program that can take a simple fasta file representing a genomic locus and add mutations including indels? Ideally, we are looking for …

Hello experts, I was reading > 'Bierne, Nicolas, and Adam Eyre-Walker. "The problem of counting sites in the estimation of the synonymous and nonsynonymous substitution …

Hi, I have a collection of sequences with collection date, I want to calculate synonymous and nonsynonymous substitution per site per year. I imagine there …

Hi all, Recently I have been very interested in calculating the dN/dS ratio to estimate rates of nonsynonymous and synonymous substitutions. Since I've just started …

Hey somebody knows a simple tool for windows to calculate standard statistics for a given alignment like synonymous/nonsynonymous substitutions , transversion / transition ratio etc.... …

Hi all When analyzing mutation in exome-seq for cancer, it is obvious that non-synonymous mutations is much highly likely to be relevant to cancer-disease than …

<p>Hi all,</p> <p>I want to set transition/transversion stepmatrices during doing phylogenetic analysis. Can anyone tell me how to make it? Is there an easier way …

<p>Hi,</p> <p>I was doing QC for my paired-end exome data which is in FASTQ format. I used FASTQC for the QC but I am more …

<p>Someone suggested me that the ratio between Mean non-synonymous substitutions per non-synonymous site (dN) and Mean synonymous substitutions per synonymous site (dS) should be calculated …