I have one VCF file which contain SNPs calls with annotation. Currently, I am trying to figure out how to detect SNPs changing protein structure. Any tools are recommended?
Thank you so much.
Hi, currently I have a sequence, and am trying to find out conserved non-coding sequence across vertebrate species, such as human, mus, dog, chicken. Can …
Hello, I'm trying to generate new reference annatoation file(GTF) of sub-population (or ecotype). Currently, I have reference genome annotation file(GTF) and vcf file from the …
Dear all, I am struggling with identification of large insertion/deletion as well as variants calls. I have used the GATK for snps calls and realized …
Hello, I need to convert .vcf files from 1000Genomes into FASTA files while maintaining phasing. I currently am doing this more or less manually using …
<p>Hi All,</p> <p>I'm new to protein structural modeling and am trying to figure out how to build a model incorporating quaternary structure, assuming a multimeric …
Hello shangzhenhua08!
We believe that this post does not fit the main topic of this site.
this question has been asked many times. eg: Get Amino Acid Changes From Snp Calls search this site for VEP and/or SNPEFF
For this reason we have closed your question. This allows us to keep the site focused on the topics that the community can help with.
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Cheers!
if my previous answer was of help ( freebayes issue for BAM file ) , you should validate+close it : (green mark on the left of my answer)