Effect Allele Frequency (EAF) to Minor Allele Frequency (MAF)

Question

[bigfoot]

How could I convert the Effect Allele Frequency (EAF) to Minor Allele Frequency (MAF) in GWAS summary statistics?

Answer 1

[Kevin Blighe]

Hello and good evening or morning, depending on your location.

First, please define [and understand] what is the 'effect allele' - it may already be the minor allele. Also, please read my previous answer, here: A: Definition of minor and major allele and connection with risk, effect, wildtype

Kevin