Effect Allele Frequency (EAF) to Minor Allele Frequency (MAF)
How could I convert the Effect Allele Frequency (EAF) to Minor Allele Frequency (MAF) in GWAS summary statistics?
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Kevin Blighe
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bigfoot •
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bigfoot •
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Hello and good evening or morning, depending on your location.
First, please define [and understand] what is the 'effect allele' - it may already be the minor allele. Also, please read my previous answer, here: A: Definition of minor and major allele and connection with risk, effect, wildtype
Kevin
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