pathway related to specified gene
Dear all,
I recently found a gene highly regulated during a disease I am interested in.
I would like to find all correlated genes and group the significantly correlated genes in pathway using a known database such as REACTOME.
The idea is to link the dysregulated gene I found to other major pathways well documented to be regulated during the disease.
In my head, I would see my interesting gene in the center of a plot and all the correlated genes around, sorted by pathway.
Would anyone have an idea to perform this kind of analysis?
thank you very much David
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Not sure if this would help : I tried doing something similar using Cytoscape, I had a "node" of interest and I was able to extract associated interactions of that node from various different datasets (so a network which is formed by extracting information associated with my "node" of interest from various other datasets). Maybe you could try something along those lines?