This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Convolution and deconvolution in gene expression

Hi All,

I am trying to understand the mathematical concept behind convolution and deconvolution in gene expression. Went through various papers but they are way too complicated. Can anyone provide simple mathematical explanation.

Thanks for your help in advance.

gene

1 answer

This is a good paper to go through

Wang, X., Park, J., Susztak, K., Zhang, N. R., & Li, M. (2019). Bulk tissue cell type deconvolution with multi-subject single-cell expression reference. Nature communications, 10(1), 1-9.

Link: https://www.nature.com/articles/s41467-018-08023-x

enter image description here

Log in to answer this question.