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how can i find differentailly expressed genes between two data set?

i have two data set of miRNA raw reads counts,both files contain 96 samples. one data set is normal and another one is diseased data set. how can i find differentially expressed genes via comparing these two data set. how can i differentially expressed genes.?

differentialy expressed genes r rna-seq

Hello husainbioinfos!

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i gone through DESeq2 package but still didn't get it.

You need to be more specific here.

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Yes. I think so. You asked many questions which were so hard to instruct as describing text whereas some threads showed you had no experiences at all about bioinformatics. The best advice is to look for a local bioinformatician who can give you a step-by-step guide.

i gone through DESeq2 package but still didn't get it.

You need to find a friendly local informatician who can help guide you. Transcriptomics is tricky at the best of times, and the forum should not be a substitute for local expertise who can really guide your project.

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