You could try GenSAS. It has all the tools needed to do a de-novo annotation. It uses BRAKER instead of MAKER, but therefore everything is integrated into a single web-frontend with a step-by-step work-flow.
Hello All, I am presently working with histone modification of mouse genome. I am quite familiar with the histone modification data available in the UCSC …
Since you added
makeras a tag you obviously know about that program. It would probably be the best bet to start with.