I have a few data objects that are the result of an analysis producing regression models associated with methylation for TCGA GBM and LGG subjects. I am trying to figure out how I can use R to find out which probes among these data objects correlate with patient survival? With this information, I hope to establish if the gene MGMT is one of the genes whose methylation show an association with survival. Is there a general procedure that I might look to as a guide for this? I believe the result of such a query into probeset data would result in a heatmap visualizing the association with survival.

thanks,

Spencer