I am using GBM and LGG tumors data from GCD, I have refereed to the TCGAworlflow, TCGAbiolink packages.
I want to compare the mutations between GBM and LGG tumor data. I know maftools is for the mutation analysis.
I was following this tutorial (https://www.bioconductor.org/help/workflows/TCGAWorkflow/)
where it combines the mutation information of GBM and LGG data and then it gives the summary plot of mutations using maftools.
So my question is,
is there a way to compare the mutations between two datasets, here for example: GBM and LGG ?
and if there is a way to do such comparison, then can anyone explain me this with a sample R code?