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Gene clustering with OrthoMCL

Hi, I would like to run OrthoMCL and as input, it requires protein sequences from desired organisms. Does OrthoMCL use assembled transcript from RNA-Seq?

Thank you in advance,

gene cluster rna-seq protein

OrthoMCL is an orthologue clustering tool for defining core genomes/pangenomes etc. In theory you could use it with CDSs extracted from assembled transcripts, but I don't really see why you would do this (unless I'm missing something).

What are you trying to achieve?

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