Question

Why there is no beta of SE output in some meta GWAS results?

0

Entering edit mode

5.1 years ago

lilingjoyo ▴ 40

Hi all,

I want to use a summary statistics of a meta GWAS result. The meta analysis was performed by using META. In the summary statistic table, there are z-score and p-value columns, but no beta or SE columns. But I need beta as my input. Here is header of the summary table

SNP CHR BP  Allele1 Allele2 N   Zscore  P

I know that the conversion between beta and zscore is that:

zscore = beta / SE

How could I calculate beta based on provided info?

gwas meta beta SE • 3.1k views

ADD COMMENT • link updated 3.2 years ago by DM ▴ 40 • written 5.1 years ago by lilingjoyo ▴ 40

0

Entering edit mode

Do you mean METAL software?

ADD REPLY • link 5.1 years ago by zx8754 11k

0

Entering edit mode

Sorry, spelling mistake. Yeah, it's METAL.

ADD REPLY • link 5.1 years ago by lilingjoyo ▴ 40

score 1 · Answer 1 · 2021-02-01

1

Entering edit mode

3.2 years ago

DM ▴ 40