SPANR result interpretation

Question

[nkausthu]

Hi,

I have an intronic variant which lies ~70bp upstream of an exon and I have used splicing-based Analysis of Variants (SPANR) to know the impact of a an intronic variant. Unfortunately, I am unable to interpret the results given and not able to find any tutorial regarding the tool. It would be really great if someone can give suggestions on this or suggest any other tools which can be used for the same (other than mutationtaster, HSF, Intsplice,Netgene2). Thank you

Answer 1

[Kevin Blighe]

You have not pasted the results here, so, nobody can comment. If you must use SPANR, then consider contacting the author(s) of the program.

I list some other splice predictors here:

• A: How to choose good tools for identifying functional SNPs?
• A: pathogenicity predictors of cancer mutations